Features of the course of relapsing polychondritis (clinical case) 

Olga G. Radaykina, Candidate of medical sciences, associate professor, associate professor of the sub-department of faculty therapy with a course in medical rehabilitation, Medical Institute, Ogarev Mordovia State University (68 Bolshevistskaya street, Saransk, Russia), E-mail: mrsolga5@yandex.ru
Anna A. Usanova, Doctor of medical sciences, professor, head of the sub-department of faculty therapy with a course in medical rehabilitation, Medical Institute, Ogarev Mordovia State University (68 Bolshevistskaya street, Saransk, Russia), E-mail: anna61-u@mail.ru
Irina Kh. Fazlova, Candidate of medical sciences, associate professor, associate professor of the sub-department of faculty therapy with a course of medical rehabilitation, Medical Institute, Ogarev Mordovia State University (68 Bolshevistskaya street, Saransk, Russia), E-mail: fazlova@inbox.ru
Natalya N. Guranova, Candidate of medical sciences, associate professor, associate professor of the sub-department of faculty therapy with a course of medical rehabilitation, Medical Institute, Ogarev Mordovia State University (68 Bolshevistskaya street, Saransk, Russia), E-mail: nguranova@mail.ru
Ekaterina V. Veshkina, Resident of the sub-department of outpatient and polyclinic therapy, Medical Institute, Ogarev Mordovia State University (68 Bolshevistskaya street, Saransk, Russia), E-mail: ekaterinaveshkina@inbox.ru

Relapsing polychondritis is a rare disease of autoimmune nature. At this stage, the problems of understanding the pathophysiology of relapsing polychondritis, its diagnosis, assessment of activity and prognosis, as well as treatment have not been resolved. The disease develops through exacerbation of remissions. It is characterized by clinical polymorphism, requiring a team approach from specialists from different specialties. Manifesta-tions usually occur gradually over time, and their frequency depends on the duration, activity and severity of the disease. Clinical heterogeneity of the disease is a source of diagnostic errors. The differential diagnosis in most cases concerns the involvement of each organ, which may appear immediately in a particular patient, but in most cases appears gradually, with an average of two symptoms at the onset of the disease. Purpose of the study: analysis of a clinical case of relapsing polychondritis, the clinical picture, the need for early diagnosis and the prescription of pathogenetic therapy. The article discusses our own clinical observation of relapsing polychondritis identified in a 62-year-old patient. A differential diagnosis was made between the patient’s disease, systemic scleroderma and necrotizing vasculitis.

relapsing polychondritis, diagnostics, systemic scleroderma, necrotizing vasculitis, COVID-19

Radaykina O.G., Usanova A.A., Fazlova I.Kh., Guranova N.N., Veshkina E.V. Features of the course of relapsing polychondritis (clinical case). Izvestiya vysshikh uchebnykh zavedeniy. Povolzhskiy region. Meditsinskie nauki = University proceedings. Volga region. Medical sciences. 2025;(1):89–98. (In Russ.). doi: 10.21685/2072-3032-2025-1-7